Article
Genes on rat chromosomes 3, 5, 10, and 16 are linked with facets of metabolic syndrome.
Obesity (Silver Spring, Md.) - 1 Jun 2009
Baguhl Romy, Wilke Barbara, Klöting Nora, Klöting Ingrid
Abstract excerpt
WOKW (Wistar Ottawa Karlsburg W) rats develop metabolic syndrome closely resembling human disorder. In crossing studies between disease-prone WOKW and disease-resistant DA (Dark Agouti) rats, several quantitative trait loci (QTLs) were mapped. To prove the in vivo relevance of QTLs, congenic DA.WOKW rats, briefly termed DA.3aW, DA.3bW, DA.5W, DA.10W, and DA.16W, were generated by transferring chromosomal regions...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
