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Pre-Analytical Conditions in Non-Invasive Prenatal Testing of Cell-Free Fetal RHD

18 Oct 2013

Abstract excerpt

BACKGROUND: Non-invasive prenatal testing of cell-free fetal DNA (cffDNA) in maternal plasma can predict the fetal RhD type in D negative pregnant women. In Denmark, routine antenatal screening for the fetal RhD gene (RHD) directs the administration of antenatal anti-D prophylaxis only to women who carry an RhD positive fetus. Prophylaxis reduces the risk of immunization that may lead to hemolytic disease of the...

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PMID: 24204719
DOI: 10.1371/journal.pone.0076990

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