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Article

Two DNA repair gene polymorphisms on the risk of gastrointestinal cancers: a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2014

Hu Yue, Zhou Min, Li Kang, Zhang Kai, Kong Xiangquan, Zheng Yamei, Li Jianxu, Liu Li

Abstract excerpt

PARP-1 and MGMT play an important role in the DNA repair system and therefore have been implicated in human carcinogenesis. However, the association between the most studied PARP-1 rs1136410: T > C and MGMT rs12917: C > T polymorphism and risk of gastrointestinal (GI) cancers was reported with inconclusive results. Accordingly, a meta-analysis of 23 published case-control studies was conducted to assess the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Modification Methylases
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Share to Poly (ADP-Ribose) Polymerase-1
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Source

Identifiers

PMID: 24203816
DOI: 10.1007/s13277-013-1320-z

Genes

MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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