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Article

Pleiotropic effects of TCF7L2 gene variants and its modulation in the metabolic syndrome: from the LIPGENE study.

Atherosclerosis - 1 Jan 2011

Delgado-Lista J, Perez-Martinez P, García-Rios A, Phillips C M, Williams C M, Gulseth H L, Helal O, Blaak E E, Kiec-Wilk B, Basu S, Drevon C A, Defoort C, Saris W H, Wybranska I, Riserus U, Lovegrove J A, Roche H M, Lopez-Miranda J

Abstract excerpt

AIMS/HYPOTHESIS: Variants of the TCF7L2 gene predict the development of type 2 diabetes mellitus (T2DM). We investigated the associations between gene variants of TCF7L2 and clinical features of the metabolic syndrome (MetS) (an entity often preceding T2DM), and their interaction with non-genetic...

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Identifiers

PMID: 21115178
DOI: 10.1016/j.atherosclerosis.2010.10.027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21115178-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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