Article
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
Diabetes - 1 Apr 2011
Kraja Aldi T, Vaidya Dhananjay, Pankow James S, Goodarzi Mark O, Assimes Themistocles L, Kullo Iftikhar J, Sovio Ulla, Mathias Rasika A, Sun Yan V, Franceschini Nora, Absher Devin, Li Guo, Zhang Qunyuan, Feitosa Mary F, Glazer Nicole L, Haritunians Talin, Hartikainen Anna-Liisa, Knowles Joshua W, North Kari E, Iribarren Carlos, Kral Brian, Yanek Lisa, O'Reilly Paul F, McCarthy Mark I, Jaquish Cashell, Couper David J, Chakravarti Aravinda, Psaty Bruce M, Becker Lewis C, Province Michael A, Boerwinkle Eric, Quertermous Thomas, Palotie Leena, Jarvelin Marjo-Riitta, Becker Diane M, Kardia Sharon L R, Rotter Jerome I, Chen Yii-Der Ida, Borecki Ingrid B
Abstract excerpt
OBJECTIVE The metabolic syndrome (MetS) is defined as concomitant disorders of lipid and glucose metabolism, central obesity, and high blood pressure, with an increased risk of type 2 diabetes and cardiovascular disease. This study tests whether common genetic variants with pleiotropic effects account for some of the correlated architecture among five metabolic phenotypes that define MetS. RESEARCH DESIGN AND...
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