Article
Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya.
Malaria journal - 8 Nov 2005
Thathy Vandana, Moulds JoAnn M, Guyah Bernard, Otieno Walter, Stoute José A
Abstract excerpt
BACKGROUND: It has been hypothesized that the African alleles Sl2 and McCb of the Swain-Langley (Sl) and McCoy (McC) blood group antigens of the complement receptor 1 (CR1) may confer a survival advantage in the setting of Plasmodium falciparum malaria, but this has not been demonstrated. METHODS: To test this hypothesis, children in western Kenya with severe malaria-associated anaemia or cerebral malaria were...
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