Article
CR1 Knops blood group alleles are not associated with severe malaria in the Gambia.
Genes and immunity - 1 Jul 2003
Zimmerman P A, Fitness J, Moulds J M, McNamara D T, Kasehagen L J, Rowe J Alexandra, Hill A V S
Abstract excerpt
The Knops blood group antigen erythrocyte polymorphisms have been associated with reduced falciparum malaria-based in vitro rosette formation (putative malaria virulence factor). Having previously identified single-nucleotide polymorphisms (SNPs) in the human complement receptor 1 (CR1/CD35) gene underlying the Knops antithetical antigens Sl1/Sl2 and McC(a)/McC(b), we have now performed genotype comparisons to...
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