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Article

Identification of the Kna/Knb polymorphism and a method for Knops genotyping.

Transfusion - 1 Feb 2004

Moulds J M, Thomas B J, Doumbo O, Diallo D A, Lyke K E, Plowe C V, Rowe J A, Birmingham D J

Abstract excerpt

BACKGROUND: DNA mutations resulting in the McCoy and Swain-Langley polymorphisms have been identified on complement receptor 1 (CR1)-a ligand for rosetting of Plasmodium falciparum-infected RBCs. The molecular identification of the Kna/Knb polymorphism was sought to develop a genotyping method for use in the study of the Knops blood group and malaria. STUDY DESIGN AND METHODS: CR1 deletion constructs were used in...

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Identifiers

PMID: 14962306
DOI: 10.1111/j.1537-2995.2004.00615.x
PMCID: PMC2877259

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Related research

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Research trail→

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Identification of the Kna/Knb polymorphism and a method for Knops genotyping.PMID 14962306Read ↗

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Lack of evidence from studies of soluble protein fragments that Knops blood group polymorphisms in complement receptor-type 1 are driven by malaria.Semantic proximity Read ↗

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