Article
A hypothesis-driven association study of 28 nuclear-encoded mitochondrial genes with antipsychotic-induced weight gain in schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 May 2014
Gonçalves Vanessa F, Zai Clement C, Tiwari Arun K, Brandl Eva J, Derkach Andriy, Meltzer Herbert Y, Lieberman Jeffrey A, Müller Daniel J, Sun Lei, Kennedy James L
Abstract excerpt
Mitochondria are the main source of energy for neurons and have a role in many vital neuronal functions. Mitochondrial dysfunction has been described in schizophrenia, and antipsychotics such as clozapine and olanzapine have been associated with differences in gene expression in mitochondria. We investigated the hypothesis that nuclear-encoded mitochondrial genes, particularly those involved in oxidative...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
