Article
Genetic variants in IGF-I, IGF-II, IGFBP-3, and adiponectin genes and colon cancer risk in African Americans and Whites.
Cancer causes & control : CCC - 1 Jul 2012
Keku Temitope O, Vidal Adriana, Oliver Shannon, Hoyo Catherine, Hall Ingrid J, Omofoye Oluwaseun, McDoom Maya, Worley Kendra, Galanko Joseph, Sandler Robert S, Millikan Robert
Abstract excerpt
PURPOSE: Evaluating genetic susceptibility may clarify effects of known environmental factors and also identify individuals at high risk. We evaluated the association of four insulin-related pathway gene polymorphisms in insulin-like growth factor-1 (IGF-I) (CA)( n ) repeat, insulin-like growth factor-2 (IGF-II) (rs680), insulin-like growth factor-binding protein-3 (IGFBP-3) (rs2854744), and adiponectin (APM1...
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