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Article

Energy balance, insulin-related genes and risk of colon and rectal cancer.

International journal of cancer - 20 May 2005

Slattery Martha L, Murtaugh Maureen, Caan Bette, Ma Khe Ni, Neuhausen Susan, Samowitz Wade

Abstract excerpt

Energy balance, or the ability to maintain body weight by balancing energy intake with energy expenditure, appears to be important in the etiology of colon cancer. One possible mechanism whereby energy balance may be associated with colorectal cancer is through its association with insulin. In our study, we evaluate the interaction between polymorphisms in 4 genes thought to be involved in insulin-related...

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Share to Colonic Neoplasms
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Share to Insulin-Like Growth Factor Binding Protein 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor I

Share to Insulin Receptor Substrate Proteins

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Source

Identifiers

PMID: 15688407
DOI: 10.1002/ijc.20843

Genes

IGF1
IRS2
IGFBP3
IRS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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