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Article

IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites.

Disease markers - 1 Jan 2012

Hoyo Cathrine, Murphy Susan K, Schildkraut Joellen M, Vidal Adriana C, Skaar David, Millikan Robert C, Galanko Joseph, Sandler Robert S, Jirtle Randy, Keku Temitope

Abstract excerpt

The Mannose 6 Phosphate/Insulin-like Growth Factor Receptor-2 (IGF2R) encodes a type-1 membrane protein that modulates availability of the potent mitogen, IGF2. We evaluated the associations between IGF2R non-synonymous genetic variants (c.5002G>A, Gly1619Arg(rs629849), and c.901C>G, Leu252Val(rs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22377707
DOI: 10.3233/DMA-2011-0865
PMCID: PMC3751395

Genes

IGF2R
IGF2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22377707-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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