Article
Epigenetic Regulation in Etiology of Type 1 Diabetes Mellitus.
International journal of molecular sciences - 19 Dec 2019
Cerna Marie
Abstract excerpt
Type 1 diabetes mellitus (T1DM) is caused by an autoimmune destruction of the pancreatic β-cells, a process in which autoreactive T cells play a pivotal role, and it is characterized by islet autoantibodies. Consequent hyperglycemia is requiring lifelong insulin replacement therapy. T1DM is caused by the interaction of multiple environmental and genetic factors. The integrations of environments and genes occur...
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