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Article

Effects of tetrandrine on glioma cell malignant phenotype via inhibition of ADAM17.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2014

Wu Zhichao, Wang Guangzhi, Xu Shaoqian, Li Yang, Tian Yu, Niu Hongshuang, Yuan Fei, Zhou Fenggang, Hao Zhen, Zheng Yongri, Li Qingsong, Wang Jianjiao

Abstract excerpt

Tetrandrine (TET), a bisbenzylisoquinoline alkaloid isolated from the root of Hang-Fang-Chi (Stephania tetrandra S. Moore), exhibits broad pharmacological effects, including antitumor activity in various malignant neoplasms. Recently, the beneficial effects of TET on cytotoxicity towards tumor cells, radiosensitization, circumventing multidrug resistance, normal tissue radioprotection, and antiangiogenesis have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24185966
DOI: 10.1007/s13277-013-1293-y

Genes

ADAM17
EGFR
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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