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Article

Probabilistic model based error correction in a set of various mutant sequences analyzed by next-generation sequencing.

Computational biology and chemistry - 1 Dec 2013

Aita Takuyo, Ichihashi Norikazu, Yomo Tetsuya

Abstract excerpt

To analyze the evolutionary dynamics of a mutant population in an evolutionary experiment, it is necessary to sequence a vast number of mutants by high-throughput (next-generation) sequencing technologies, which enable rapid and parallel analysis of multikilobase sequences. However, the observed sequences include many errors of base call. Therefore, if next-generation sequencing is applied to analysis of a...

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PMID: 24184706
DOI: 10.1016/j.compbiolchem.2013.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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