Article
Quality control test for sequence-phenotype assignments.
PloS one - 1 Jan 2015
Ortiz Maria Teresa Lara, Rosario Pablo Benjamín Leon, Luna-Nevarez Pablo, Gamez Alba Savin, Martínez-del Campo Ana, Del Rio Gabriel
Abstract excerpt
Relating a gene mutation to a phenotype is a common task in different disciplines such as protein biochemistry. In this endeavour, it is common to find false relationships arising from mutations introduced by cells that may be depurated using a phenotypic assay; yet, such phenotypic assays may introduce additional false relationships arising from experimental errors. Here we introduce the use of high-throughput...
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