ABCC4 is required for cell proliferation and tumorigenesis in non-small cell lung cancer

Abstract excerpt

BACKGROUND: Multidrug resistance protein 4 (MRP4), also known as ATP-cassette binding protein 4 (ABCC4), is a member of the MRP/ABCC subfamily of ATP-binding cassette transporters, which are capable of pumping a wide variety of drugs out of the cell. However, little is known about the function of ABCC4 in the proliferation of lung cancer cells. METHODS: ABCC4 mRNA and protein levels in lung cancer cell lines were...

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