Article
Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal.
BMC genetics - 31 Oct 2013
Mullin Benjamin H, Mamotte Cyril, Prince Richard L, Spector Tim D, Dudbridge Frank, Wilson Scott G
Abstract excerpt
BACKGROUND: Low bone mineral density (BMD) is a primary risk factor for osteoporosis and is a highly heritable trait, but appears to be influenced by many genes. Genome-wide linkage studies have highlighted the chromosomal region 3p14-p22 as a quantitative trait locus for BMD (LOD 1.1 - 3.5). The...
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