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Article

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Dec 2009

Yerges Laura M, Klei Lambertus, Cauley Jane A, Roeder Kathryn, Kammerer Candace M, Moffett Susan P, Ensrud Kristine E, Nestlerode Cara S, Marshall Lynn M, Hoffman Andrew R, Lewis Cora, Lang Thomas F, Barrett-Connor Elizabeth, Ferrell Robert E, Orwoll Eric S, Zmuda Joseph M

Abstract excerpt

Genetics is a well-established but poorly understood determinant of BMD. Whereas some genetic variants may influence BMD throughout the body, others may be skeletal site specific. We initially screened for associations between 4608 tagging and potentially functional single nucleotide polymorphisms (SNPs) in 383 candidate genes and femoral neck and lumbar spine volumetric BMD (vBMD) measured from QCT scans among...

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Source

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Identifiers

PMID: 19453261
DOI: 10.1359/jbmr.090524
PMCID: PMC2791518

Genes

APC
DMP1
FGFR2
FLT1
FOXC2
IGFBP2
NFATC1
PTN
SOST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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