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Article

Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Dec 2009

Wilson Scott G, Jones Michelle R, Mullin Ben H, Dick Ian M, Richards J Brent, Pastinen Tomi M, Grundberg Elin, Ljunggren Osten, Surdulescu Gabriela L, Dudbridge Frank, Elliott Katherine S, Cervino Alessandra C L, Spector Timothy D, Prince Richard L

Abstract excerpt

Previous data from our group indicate that BMD is linked to chromosome 3p14-p21. Because the filamin B (FLNB gene resides in this region, is the cause of skeletal dysplasias, and was identified among the top genes in our bioinformatics analysis, we hypothesized a role for FLNB in the regulation of bone structure in the general population. Using a tag single nucleotide polymorphism (SNP) approach, a family study...

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Identifiers

PMID: 19453265
DOI: 10.1359/jbmr.090530

Genes

FLNB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro.PMID 19453265Read ↗

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