Article
Single nucleotide polymorphisms in new candidate genes are associated with bone mineral density and fracture risk.
European journal of endocrinology - 1 Aug 2008
Lazáry Aron, Kósa János P, Tóbiás Bálint, Lazáry Judit, Balla Bernadett, Bácsi Krisztián, Takács István, Nagy Zsolt, Mezo Tibor, Speer Gábor, Lakatos Péter
Abstract excerpt
OBJECTIVE: Osteoporosis (OP) is a multifactorial disease with high heritability but its exact genetic background is still poorly understood. We examined the effect of 24 single nucleotide polymorphisms (SNPs) located in five genes--alkaline phosphatase, matrix metalloproteinase-2, tissue inhibitor of metalloproteases-2 (TIMP2), fibroblast growth factor receptor-1 (FGFR1), and fatty acid-binding protein-3...
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