Article

Bayesian Modeling of Epigenetic Variation in Multiple Human Cell Types

2015-04-13

Abstract excerpt

With massive amount of sequencing data generated for many epigenetic features in a variety of cell and tissue types, the chief challenges are to build effective and quantitative models explaining how the dynamics in multiple epigenomes lead to differential gene expression and diverse phenotypes. We developed a unified Bayesian framework for jointly annotating multiple epigenomes and detecting differential regulati...

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Literature Corpus work: b7411bca-d2cc-54d3-b678-83ffac9cad72
DOI: 10.1101/018028

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