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Article

Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria.

Molecular endocrinology (Baltimore, Md.) - 1 Feb 2005

Hauet Thierry, Yao Zhi-Xing, Bose Himangshu S, Wall Christopher T, Han Zeqiu, Li Wenping, Hales Dale B, Miller Walter L, Culty Martine, Papadopoulos Vassilios

Abstract excerpt

Hormone-induced steroid biosynthesis begins with the transfer of cholesterol from intracellular stores into mitochondria. Steroidogenic acute regulatory protein (StAR) and peripheral-type benzodiazepine receptor (PBR) have been implicated in this rate-determining step of steroidogenesis. MA-10 mouse Leydig tumor cells were treated with and without oligodeoxynucleotides (ODNs) antisense to PBR and StAR followed by...

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Identifiers

PMID: 15498831
DOI: 10.1210/me.2004-0307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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