Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gremlin1 promotes carcinogenesis of glioma in vitro

8 Nov 2016

Abstract excerpt

As the most prevalent and lethal type of brain tumours, gliomas, especially malignant ones, are relatively resistant to conventional therapies. Gremlin 1 (GREM1) is a secreted glycoprotein that is implicated in the maintenance of cancer stem cells in tumour hierarchy. In the current study, the role of GREM1 in the carcinogenesis of glioma was studied using a knockdown approach. We first examined the expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to MicroRNA in disease regulation
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27862197
DOI: 10.1111/1440-1681.12697

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gremlin1 promotes carcinogenesis of glioma in vitroPMID 27862197Read ↗

Current status and prospects of GREM1 research in cancer (Review)Semantic proximity Read ↗

Up-regulation of miR-663a inhibits the cancer stem cell-like properties of glioma via repressing the KDM2A-mediated TGF-β/SMAD signaling pathwaySemantic proximity Read ↗

Knockdown GREM1 suppresses cell growth, angiogenesis, and epithelial‐mesenchymal transition in colon cancerSemantic proximity Read ↗

Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44Semantic proximity Read ↗

Insights into the Role of Gremlin-1, a Bone Morphogenic Protein Antagonist, in Cancer Initiation and ProgressionSemantic proximity Read ↗

LRG1 modulates invasion and migration of glioma cell lines through TGF-β signaling pathwaySemantic proximity Read ↗

Decreased BRMS1L expression is correlated with glioma grade and predicts poor survival in glioblastoma via an invasive phenotype.Semantic proximity Read ↗

Genomics and Prognosis Analysis of Epithelial-Mesenchymal Transition in GliomaSemantic proximity Read ↗

Knockdown of LGR5 suppresses the proliferation of glioma cells in vitro and in vivoSemantic proximity Read ↗

The miR-192-EGR1/HOXB9 Loop Regulates Glioma Cell Stemness and Malignant Phenotypes by Promoting Their Mesenchymal Transition.Semantic proximity Read ↗

LncRNA SNHG1 facilitates the epithelial-mesenchymal transition and invasiveness in glioblastoma multiforme via regulation of the miR-128-3p/RRAS2 axisSemantic proximity Read ↗

Early growth response 1 promoted the invasion of glioblastoma multiforme by elevating HMGB1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.