Article
Impact of TRPV3 on the development of allergic dermatitis as a dendritic cell modulator.
Experimental dermatology - 1 Dec 2013
Yamamoto-Kasai Erika, Yasui Kiyoshi, Shichijo Michitaka, Sakata Tsuneaki, Yoshioka Takeshi
Abstract excerpt
The transient receptor potential channel vanilloid subfamily V member 3 (TRPV3), which functions as a thermosensor in keratinocytes, plays an important role in the development of allergic and itchy dermatitis in rodents. Although real-time PCR analysis using lesional and non-lesional skin samples from patients with atopic dermatitis showed that TRPV3 was expressed in lesional skin, the role that TRPV3 plays in...
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