Article
Replication fork reversal after replication-transcription collision.
PLoS genetics - 1 Jan 2012
De Septenville Anne L, Duigou Stéphane, Boubakri Hasna, Michel Bénédicte
Abstract excerpt
Replication fork arrest is a recognized source of genetic instability, and transcription is one of the most prominent causes of replication impediment. We analyze here the requirement for recombination proteins in Escherichia coli when replication-transcription head-on collisions are induced at a specific site by the inversion of a highly expressed ribosomal operon (rrn). RecBC is the only recombination protein...
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