Article
Delineation of the TRAK binding regions of the kinesin-1 motor proteins.
FEBS letters - 29 Nov 2013
Randall Thomas S, Moores Carolyn, Stephenson F Anne
Abstract excerpt
Understanding specific cargo distribution in differentiated cells is a major challenge. Trafficking kinesin proteins (TRAKs) are kinesin adaptors. They bind the cargo binding domain of kinesin-1 motor proteins forming a link between the motor and their cargoes. To refine the TRAK1/2 binding sites within the kinesin-1 cargo domain, rationally designed C-terminal truncations of KIF5A and KIF5C were generated and...
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