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Article

Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins.

The Journal of biological chemistry - 12 Jan 2018

Guo Qiong, Liao Shanhui, Zhu Zhongliang, Li Yue, Li Fudong, Xu Chao

Abstract excerpt

A well-controlled microtubule organization is essential for intracellular transport, cytoskeleton maintenance, and cell development. KN motif and ankyrin repeat domain-containing protein 1 (KANK1), a member of KANK family, recruits kinesin family member 21A (KIF21A) to the cell cortex to control microtubule growth via its C-terminal ankyrin domain. However, how the KANK1 ankyrin domain recognizes KIF21A and...

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Identifiers

PMID: 29183992
DOI: 10.1074/jbc.M117.817494
PMCID: PMC5767861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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