Article
The impact of the genome-wide supported variant in the cyclin M2 gene on gray matter morphology in schizophrenia.
Behavioral and brain functions : BBF - 25 Oct 2013
Ohi Kazutaka, Hashimoto Ryota, Yamamori Hidenaga, Yasuda Yuka, Fujimoto Michiko, Umeda-Yano Satomi, Fukunaga Masaki, Watanabe Yoshiyuki, Iwase Masao, Kazui Hiroaki, Takeda Masatoshi
Abstract excerpt
BACKGROUND: Genome-wide significant associations of schizophrenia with eight SNPs in the CNNM2, MIR137, PCGEM1, TRIM26, CSMD1, MMP16, NT5C2 and CCDC68 genes have been identified in a recent mega-analysis of genome-wide association studies. To date, the role of these SNPs on gray matter (GM) volumes remains unclear. METHODS: After performing quality control for minor-allele frequency > 5% using a JPT HapMap sample...
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