Article
Genome-wide genotype-based risk model for survival in acute myeloid leukaemia patients with normal karyotype.
British journal of haematology - 1 Oct 2013
Choi Hangseok, Jung Chulwon, Sohn Sang Kyun, Kim Seonwoo, Kim Hyeoung-Joon, Kim Yeo-Kyeoung, Kim TaeHyung, Zhang Zhaolei, Shin Eun-Soon, Lee Jong-Eun, Moon Joon Ho, Kim Sung Hyun, Kim Kyoung Ha, Mun Yeung-Chul, Kim Hawk, Park Jinny, Kim Jhingook, Kim Dennis
Abstract excerpt
Single nucleotide polymorphisms (SNP) are inter-individual genetic variations that could explain inter-individual differences of response/survival to chemotherapy. The present study was performed to build up a risk model for survival in 247 patients with acute myeloid leukaemia (AML) with normal karyotype (AML-NK). Genome-wide Affymetrix SNP array 6.0 was used for genotyping in discovery set (n = 118). After...
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