Article
Gene expression profiling in the leukemic stem cell-enriched CD34+ fraction identifies target genes that predict prognosis in normal karyotype AML.
Leukemia - 1 Dec 2011
de Jonge H J M, Woolthuis C M, Vos A Z, Mulder A, van den Berg E, Kluin P M, van der Weide K, de Bont E S J M, Huls G, Vellenga E, Schuringa J J
Abstract excerpt
In order to identify acute myeloid leukemia (AML) CD34(+)-specific gene expression profiles, mononuclear cells from AML patients (n=46) were sorted into CD34(+) and CD34(-) subfractions, and genome-wide expression analysis was performed using Illumina BeadChip Arrays. AML CD34(+) and CD34(-) gene...
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