Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genome-wide single-nucleotide polymorphism-array can improve the prognostic stratification of the core binding factor acute myeloid leukemia.

American journal of hematology - 1 Oct 2012

Huh Jungwon, Kim Hee-Je, Jung Chul Won, Kim Hee-Jin, Kim Sun-Hee, Kim Yeo-Kyeoung, Kim Hyeoung-Joon, Shin Myung Geun, Moon Joon Ho, Sohn Sang Kyun, Kim Sung Hyun, Lee Won Sik, Won Jong Ho, Mun Yeung Chul, Kim Hawk, Park Jinny, Min Woo Sung, Kim Dong Hwan Dennis

Abstract excerpt

Core binding factor (CBF) AML with the D816 C-KIT gene mutation demonstrate inferior treatment outcomes. However, the remaining cases without the D816 C-KIT mutation imply a requirement of more sophisticated dissection of the patients according to their prognosis. In this study, we analyzed the prognostic value of a single nucleotide polymorphism array (SNP-A) based karyotyping combined with metaphase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Chromosome Inversion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Core Binding Factors

Share to Cytarabine

Share to Leukemia, Myeloid

Share to Proto-Oncogene Proteins c-kit

Share to Remission Induction

Share to Translocation, Genetic

Source

Identifiers

PMID: 22886749
DOI: 10.1002/ajh.23281

Genes

KIT
EFS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genome-wide single-nucleotide polymorphism-array can improve the prognostic stratification of the core binding factor acute myeloid leukemia.PMID 22886749Read ↗

Single-nucleotide polymorphism-array improves detection rate of genomic alterations in core-binding factor leukemia.Semantic proximity Read ↗

Genome-wide genotype-based risk model for survival in core binding factor acute myeloid leukemia patients.Semantic proximity Read ↗

Different characteristics identified by single nucleotide polymorphism array analysis in leukemia suggest the need for different application strategies depending on disease category.Semantic proximity Read ↗

Comprehensive mutational profiling of core binding factor acute myeloid leukemia.Semantic proximity Read ↗

Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication.Semantic proximity Read ↗

Adverse prognostic impact of abnormal lesions detected by genome-wide single nucleotide polymorphism array-based karyotyping analysis in acute myeloid leukemia with normal karyotype.Semantic proximity Read ↗

Advances in molecular genetics and treatment of core-binding factor acute myeloid leukemiaSemantic proximity Read ↗

Genetic abnormalities in core binding factor acute myeloid leukemia.Semantic proximity Read ↗

Gene-expression profiling identifies distinct subclasses of core binding factor acute myeloid leukemia.Semantic proximity Read ↗

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: results of the ALFA-0701 trial.Semantic proximity Read ↗

Co-occurrence of KIT and NRAS mutations defines an adverse prognostic core-binding factor acute myeloid leukemia.Semantic proximity Read ↗

Core-binding factor acute myeloid leukemia: can we improve on HiDAC consolidation?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.