Article
Differential effect of p7 inhibitors on hepatitis C virus cell-to-cell transmission.
Antiviral research - 1 Dec 2013
Meredith L W, Zitzmann N, McKeating J A
Abstract excerpt
Inhibitors targeting the hepatitis C virus (HCV) encoded viroporin, p7 prevent virus release in vitro. HCV can transmit by cell-free particle infection of new target cells and via cell-to-cell dependent contact with limited exposure to the extracellular environment. The role of assembly inhibitors in preventing HCV transmission via these pathways has not been studied. We compared the efficacy of three published...
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