Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estrogen regulates histone deacetylases to prevent cardiac hypertrophy

24 Oct 2013

Abstract excerpt

The development and progression of cardiac hypertrophy often leads to heart failure and death, and important modulators of hypertrophy include the histone deacetylase proteins (HDACs). Estrogen inhibits cardiac hypertrophy and progression in animal models and humans. We therefore investigated the influence of 17-β-estradiol on the production, localization, and functions of prohypertrophic (class I) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GDF15 and Related Biomarkers
Share to Histone Deacetylase Inhibitors Research
Share to Nuclear Receptors and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24152730
DOI: 10.1091/mbc.e13-08-0444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estrogen regulates histone deacetylases to prevent cardiac hypertrophyPMID 24152730Read ↗

Targeting histone deacetylase in cardiac diseasesSemantic proximity Read ↗

Roles and Targets of Class I and IIa Histone Deacetylases in Cardiac HypertrophySemantic proximity Read ↗

Histone deacetylase inhibition in the treatment of heart diseaseSemantic proximity Read ↗

Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen ReceptorSemantic proximity Read ↗

Role of Histone Deacetylase and Inhibitors in Cardiovascular DiseasesSemantic proximity Read ↗

Transcription Factors in Heart: Promising Therapeutic Targets in Cardiac HypertrophySemantic proximity Read ↗

Treatment with a selective histone deacetylase (HDAC) 1 and 2 inhibitor in aged mice rejuvenates multiple organ systemsSemantic proximity Read ↗

Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy.Semantic proximity Read ↗

β-Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α-PP2A-Mediated Dephosphorylation.Semantic proximity Read ↗

Histone deacetylase signaling in cardioprotectionSemantic proximity Read ↗

Selective class IIa HDAC inhibition reverses diastolic dysfunction in cardiometabolic HFpEFSemantic proximity Read ↗

HDAC-dependent ventricular remodelingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.