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Transcription Factors in Heart: Promising Therapeutic Targets in Cardiac Hypertrophy

14 Feb 2012

Abstract excerpt

Regulation of gene expression is central to cell growth, differentiation and diseases. Context specific and signal dependent regulation of gene expression is achieved to a large part by transcription factors. Cardiac transcription factors regulate heart development and are also involved in stress regulation of the adult heart, which may lead to cardiac hypertrophy. Hypertrophy of cardiac myocytes is an outcome of...

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PMID: 22758628
DOI: 10.2174/157340311799960618

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