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Article

N-cadherin promoter polymorphisms and risk of osteoarthritis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2014

Ruedel Anke, Stark Klaus, Kaufmann Simone, Bauer Richard, Reinders Joerg, Rovensky Jozef, Blazicková Stanislava, Oefner Peter J, Bosserhoff Anja K

Abstract excerpt

Osteoarthritis (OA) is the most common form of arthritis. It is characterized by cartilage destruction and bone remodeling, mediated in part by synovial fibroblasts (SFs). Given the functional significance of cadherins in these cells, we aimed at determining the role of genetic variants of N-cadherin (CDH2) in OA of the knee and hip. Six single-nucleotide polymorphisms in the genomic region of the CDH2 gene were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24148886
DOI: 10.1096/fj.13-238295

Genes

CDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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