Article
Association of common variations of the E-cadherin with endometriosis.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jan 2015
Saliminejad Kioomars, Edalatkhah Haleh, Kamali Koorosh, Memariani Toktam, Nasiri Mahbobeh, Saket Mitra, Khorram Khorshid Hamid Reza
Abstract excerpt
Endometriosis is a polygenic and multifactorial disease. E-cadherin (CDH1) gene encodes an epithelial cell-cell adhesion glycoprotein that modulates a wide variety of processes, including cell polarization, migration and cancer metastasis. Decreased expression of CDH1 in epithelial cells in peritoneal endometriosis has been reported in advanced stages of endometriotic lesions. We investigated the CDH1 -160C/A and...
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