Genetic variant of COL11A2 gene is functionally associated with developmental dysplasia of the hip in Chinese Han population.

doi:10.18632/aging.103040

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Article

Genetic variant of COL11A2 gene is functionally associated with developmental dysplasia of the hip in Chinese Han population.

Aging - 12 May 2020

Xu Renjie, Jiang Xin, Lu Junlan, Wang Kexin, Sun Ye, Zhang Yuxin

Abstract excerpt

OBJECTIVES: Developmental dysplasia of the hip (DDH) is a common skeletal disorder. This study was conducted to demonstrate the association between DDH and a polymorphism rs9277935 of COL11A2 gene. RESULTS: A significant difference in genotype distribution in a recessive model (TT+GT vs. GG) between two groups (P=0.017) was demonstrated. Analysis in female patients showed significantly greater frequency of minor...

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PMID: 32396528
DOI: 10.18632/aging.103040
PMCID: PMC7244083

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