Article
HLA associations in schizophrenia: are we re-discovering the wheel?
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2014
Kodavali Chowdari V, Watson Annie M, Prasad Konasale M, Celik Cemil, Mansour Hader, Yolken Robert H, Nimgaonkar Vishwajit L
Abstract excerpt
Associations between human leukocyte antigen (HLA) polymorphisms on chromosome 6p and schizophrenia (SZ) risk have been evaluated for over five decades. Numerous case-control studies from the candidate gene era analyzed moderately sized samples and reported nominally significant associations with several loci in the HLA region (sample sizes, n = 100-400). The risk conferred by individual alleles was modest (odds...
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