Article
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities.
Schizophrenia bulletin - 7 Sept 2023
Steen Nils Eiel, Rahman Zillur, Szabo Attila, Hindley Guy F L, Parker Nadine, Cheng Weiqiu, Lin Aihua, O'Connell Kevin S, Sheikh Mashhood A, Shadrin Alexey, Bahrami Shahram, Karthikeyan Sandeep, Hoseth Eva Z, Dale Anders M, Aukrust Pål, Smeland Olav B, Ueland Thor, Frei Oleksandr, Djurovic Srdjan, Andreassen Ole A
Abstract excerpt
BACKGROUND: Immune mechanisms are indicated in schizophrenia (SCZ). Recent genome-wide association studies (GWAS) have identified genetic variants associated with SCZ and immune-related phenotypes. Here, we use cutting edge statistical tools to identify shared genetic variants between SCZ and white blood cell (WBC) counts and further understand the role of the immune system in SCZ. STUDY DESIGN: GWAS results from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.