Impact of endothelial nitric oxide synthase gene polymorphism on severity of enterovirus 71-infection in Chinese children.

doi:10.1016/j.clinbiochem.2013.10.009

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Impact of endothelial nitric oxide synthase gene polymorphism on severity of enterovirus 71-infection in Chinese children.

Clinical biochemistry - 1 Dec 2013

Li Ji-an, Chen Zong-bo, Lv Tie-gang, Han Zhen-liang, Liu Pei-pei

Abstract excerpt

OBJECTIVES: Genetic polymorphism G894T on the endothelial nitric oxide synthase (eNOS) gene has been reported as a susceptibility factor in a number of diseases, but evidence of its effect on enterovirus 71 (EV71) infection is lacking. This study investigated the possible association between this polymorphism (rs1799983) and disease severity in Chinese children with EV71 infection. DESIGN AND METHODS: 185...

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PMID: 24140479
DOI: 10.1016/j.clinbiochem.2013.10.009

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