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Article

Correlations of PSGL-1 VNTR polymorphism with the susceptibility to severe HFMD associated with EV-71 and the immune status after infection.

Virology journal - 15 Aug 2024

Wang Xia, Qian Jing, Mi Yuqiang, Li Ying, Cao Yu, Qiao Kunyan

Abstract excerpt

Enterovirus 71 (EV-71) has strong neurotropism, and it is the main pathogen causing severe hand, foot, and mouth disease (HFMD). In clinical observations, significant differences were observed in the severity and prognosis of HFMD among children who were also infected with EV-71. Genetic differences among individuals could be one of the important causes of differences in susceptibility to EV-71-induced HFMD. As...

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Identifiers

PMID: 39148126
DOI: 10.1186/s12985-024-02461-4
PMCID: PMC11328417

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