Article
Apolipoprotein E-ε4 polymorphism and cognitive dysfunction after carotid endarterectomy.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Feb 2014
Heyer Eric J, Mergeche Joanna L, Stern Yaakov, Malone Hani R, Bruce Samuel S, Ward Justin T, Sander Connolly E
Abstract excerpt
Approximately 25% of patients undergoing carotid endarterectomy (CEA) exhibit cognitive dysfunction (CD) 1 day and 1 month after CEA. The apolipoprotein E (apoE)-ε4 polymorphism has been previously identified as a robust independent risk factor for CD 1 month after CEA. We aimed to determine whether the apoE-ε4 polymorphism is also an independent risk factor for CD as early as 1 day after CEA and to confirm the...
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