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Article

Role of APOE ε4 Allele and Incident Stroke on Cognitive Decline and Mortality.

Alzheimer disease and associated disorders - 1 Jan 2000

Rajan Kumar B, Aggarwal Neelum T, Schneider Julie A, Wilson Robert S, Everson-Rose Susan A, Evans Denis A

Abstract excerpt

BACKGROUND: The apolipoprotein E (APOE) ε4 allele and stroke increase the risk of cognitive decline. However, the association of the APOE ε4 allele before and after stroke is not well understood. METHODS: Using a prospective sample of 3444 (66% African Americans, 61% females, mean age=71.9 y) participants, we examined cognitive decline relative to stroke among those with and without the APOE ε4 allele. RESULTS:...

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Source

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Identifiers

PMID: 27849638
DOI: 10.1097/WAD.0000000000000173
PMCID: PMC5117953

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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