Article
Apolipoprotein E4 genotype increases the risk of postoperative cognitive dysfunction in patients undergoing coronary artery bypass graft surgery.
The Journal of cardiovascular surgery - 1 Aug 2006
Lelis R G B, Krieger J E, Pereira A C, Schmidt A P, Carmona M J, Oliveira S A, Auler J O C
Abstract excerpt
AIM: The aim of this study was to investigate the association between the presence of ApoE4 and the incidence of postoperative cognitive dysfunction (POCD) after cardiac surgery. METHODS: Eighty-seven adult patients undergoing elective coronary artery bypass graft surgery were observed prospectively at a university tertiary care hospital. All patients were evaluated with the Mini-Mental State Examination (MMSE)...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Apolipoprotein E4
- Apolipoproteins E
- Cognition Disorders
- Coronary Artery Bypass
- Coronary Disease
- DNA
- Female
- Follow-Up Studies
- Genotype
- Humans
- Male
- Middle Aged