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Article

APOE-epsilon4 predisposes to cognitive dysfunction following uncomplicated carotid endarterectomy.

Neurology - 13 Dec 2005

Heyer E J, Wilson D A, Sahlein D H, Mocco J, Williams S C, Sciacca R, Rampersad A, Komotar R J, Zurica J, Benvenisty A, Quest D O, Todd G, Solomon R A, Connolly E S

Abstract excerpt

BACKGROUND: Between 9% and 23% of patients undergoing otherwise uncomplicated carotid endarterectomy (CEA) develop subtle cognitive decline 1 month postoperatively. The APOE-epsilon4 allele has been associated with worse outcome following stroke. OBJECTIVE: To investigate the ability of APOE-epsilon4 to predict post-CEA neurocognitive dysfunction. METHODS: Seventy-five patients with CEA undergoing elective CEA...

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Identifiers

PMID: 16207841
DOI: 10.1212/01.wnl.0000184579.23624.6b
PMCID: PMC1524823

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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