Article
Role of sortase in Streptococcus mutans under the effect of nicotine.
International journal of oral science - 1 Dec 2013
Li Ming-Yun, Huang Rui-Jie, Zhou Xue-Dong, Gregory Richard L
Abstract excerpt
Streptococcus mutans is a common Gram-positive bacterium and plays a significant role in dental caries. Tobacco and/or nicotine have documented effects on S. mutans growth and colonization. Sortase A is used by many Gram-positive bacteria, including S. mutans, to facilitate the insertion of certain cell surface proteins, containing an LPXTGX motif such as antigen I/II. This study examined the effect of nicotine...
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