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Article

Streptococcus mutans protein synthesis during mixed-species biofilm development by high-throughput quantitative proteomics.

PloS one - 1 Jan 2012

Klein Marlise I, Xiao Jin, Lu Bingwen, Delahunty Claire M, Yates John R, Koo Hyun

Abstract excerpt

Biofilms formed on tooth surfaces are comprised of mixed microbiota enmeshed in an extracellular matrix. Oral biofilms are constantly exposed to environmental changes, which influence the microbial composition, matrix formation and expression of virulence. Streptococcus mutans and sucrose are key modulators associated with the evolution of virulent-cariogenic biofilms. In this study, we used a high-throughput...

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Identifiers

PMID: 23049864
DOI: 10.1371/journal.pone.0045795
PMCID: PMC3458072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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