Article
Consequences of a sortase A mutation in Streptococcus gordonii.
Microbiology (Reading, England) - 1 Dec 2007
Nobbs Angela H, Vajna Reka M, Johnson Jeremy R, Zhang Yongshu, Erlandsen Stanley L, Oli Monika W, Kreth Jens, Brady L Jeannine, Herzberg Mark C
Abstract excerpt
Sortase A (SrtA) is required for cell-wall anchoring of LPXTG-containing Gram-positive surface proteins. It was hypothesized, therefore, that disruption of the srtA gene would alter surface anchoring and functions of target LPXTG motif-bearing SspA and SspB proteins of Streptococcus gordonii. Mutant strains in srtA (V288srtA(-), DL1srtA(-)) were constructed in S. gordonii V288 (wtV288) and DL1 (wtDL1). When...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.