Article
Role of two single nucleotide polymorphisms in secreted frizzled related protein 1 and bladder cancer risk.
International journal of clinical and experimental pathology - 1 Jan 2013
Rogler Anja, Hoja Sabine, Socher Eileen, Nolte Elke, Wach Sven, Wieland Wolf, Hofstädter Ferdinand, Goebell Peter J, Wullich Bernd, Hartmann Arndt, Stoehr Robert
Abstract excerpt
In this study, we determined the genotype distribution of two single nucleotide polymorphisms (SNPs) in secreted frizzled related protein 1 (SFRP1), rs3242 and rs921142, in a Caucasian bladder cancer case-control study. Allelic variants of the SNPs were determined using restriction fragment length polymorphism (RFLP) analysis and partly verified by sequencing analysis. Overall, DNA from 188 consecutive and 215...
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